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Because of insufficient safety data, children, pregnant women, and nursing mothers should avoid using glucosamine.

Glucosamine may increase insulin resistance and consequently affect glucose tolerance. Individuals with diabetes who, under medical advisement, decide to use glucosamine supplements will need to monitor their blood glucose and may need to adjust the doses of the medications they take to control blood glucose. This needs to be done under medical supervision. No other drug, nutritional supplement, food, or herb interaction is known.19

There are no known drug, nutrient, food or herb interactions with chondroitin. Chitosan may form complexes with chondroitin sulfate, decreasing its absorption. Therefore, chondroitin sulfate should not be used concomitantly with chitosan.

Due to the theoretical possibility that chondroitin sulfate may have antithrombotic activity, those taking warfarin and those with hemophilia should exercise caution in its use. People who need to restrict their salt intake should, if they use chondroitin sulfate, use salt-free preparations.

No. Because of insufficient safety data, pregnant women and nursing mothers should avoid using glucosamine.

Yes. Side effects with glucosamine and chondroitin, when they occur, are mainly mild gastrointestinal complaints, such as heartburn, nausea, and diarrhea. No allergic reactions have been reported. There are no known contraindications to supplementation with either glucosamine or chondroitin.

Glucosamine may increase insulin resistance. Patients with type diabetes or those who are overweight and have problems with glucose tolerance should have their blood sugar levels carefully monitored if they use glucosamine supplements. Because of insufficient safety data, children, pregnant women, and nursing mothers should avoid using glucosamine. Due to the theoretical possibility that chondroitin sulfate may have antithrombotic activity, those taking warfarin and those with hemophilia should exercise caution in its use. People who need to restrict their salt intake should, if they use chondroitin sulfate, use salt-free preparations.

Yes, there is a large body of scientific evidence supporting the efficacy of RELAMINE. Click here to see a review of the clinical effects.

Primorine is a unique osteoarthritis-fighting compound that’s formed from a proprietary blend of para-amino benzoic acid, vitamin E, and alpha-lipoic acid.

Unlike nonprescription preparations of glucosamine and chondroitin, which can vary significantly in potency and purity—from 41% to 108% of the dosage listed on the label. RELAMINE promotes joint health with consistently high-quality ingredients. What’s more, when it’s combined with Primorine—a new kind of treatment that helps to restore cellular balance and fight osteoarthritis damage all over the body. RELAMINE provides consistent, comprehensive protection against the onset and progression of osteoarthritis.

RELAMINE contains a special combination of highly effective ingredients—glucosamine, chondroitin, and Primorine. The combination appears to interact with certain chemicals and enzymes thought to be involved in osteoarthritis. However, the precise mechanism of action of RELAMINE is unknown.

RELAMINE has been helping patients with osteoarthritis since 2006.

RELAMINE is the only therapy for osteoarthritis with two unique ingredients—pharmaceutical-grade glucosamine + chondroitin and Primorine. It is indicated for the distinct nutritional requirements of individuals under a physician's treatment for osteoarthritis.